Which dosage form is designed to pass by the digestive system and absorb through the lining of the mouth for rapid drug release?

Which dosage form is designed to pass by the digestive system and absorb through the lining of the mouth for rapid drug release?

• A. Buccal tablets
• B. Effervescent tablets
• C. Capsules
• D. Lozenges

Answer: (A)

Direct absorption through the buccal mucosa bypasses the digestive system, allowing the drug to enter the bloodstream quickly. Buccal tablets are placed in the cheek and slowly dissolve, letting the medication diffuse through the lining of the mouth into blood vessels. This route provides rapid onset and avoids first-pass metabolism in the liver, which is why it’s designed for fast drug release. In contrast, effervescent tablets dissolve in water and are swallowed, capsules travel through the GI tract, and lozenges stay in the mouth to release the drug slowly for local or prolonged effect rather than rapid systemic absorption.

Direct absorption through the buccal mucosa bypasses the digestive system, allowing the drug to enter the bloodstream quickly. Buccal tablets are placed in the cheek and slowly dissolve, letting the medication diffuse through the lining of the mouth into blood vessels. This route provides rapid onset and avoids first-pass metabolism in the liver, which is why it’s designed for fast drug release. In contrast, effervescent tablets dissolve in water and are swallowed, capsules travel through the GI tract, and lozenges stay in the mouth to release the drug slowly for local or prolonged effect rather than rapid systemic absorption.